https://berkalahayati.org/index.php/jurnal/issue/feed 2025-08-18T09:17:29+00:00 Berkala Penelitian Hayati official@berkalahayati.org Open Journal Systems <p data-start="89" data-end="112"><strong data-start="89" data-end="112">Registration Notice</strong></p> <p>Dear Prospective Authors,</p> <p>We have recently received several reports from prospective authors encountering difficulties during the registration process. Our team is actively addressing these issues to ensure a smooth experience for all users. If you experience any challenges while registering, please don’t hesitate to contact us at&nbsp;official@berkalahayati.org. We are committed to assisting you and ensuring everyone has the opportunity to submit their research findings to our journal. Thank you for your patience and understanding.</p> <p data-start="654" data-end="703"><strong>ABOUT THE JOURNAL</strong></p> <p align="justify">Berkala Penelitian Hayati is a reputable international life science journal published with both p-ISSN (0852-6834) and e-ISSN (2337-389X). It operates under the open-access model and is peer-reviewed, allowing researchers from around the world to access and contribute to its content.</p> <p align="justify">The journal was initially published semi-annually by The East Java Biological Society and was formerly in the Indonesian language. The first edition was Vol 1 No 1 in June 1995. Over the years, it has evolved and gained recognition in the academic community. In 2023, articles published three times a year, in April, August, and December, with an average of ten articles per issue. There is a record of journal accreditation:</p> <ol start="1" data-spread="false"> <li class="show"> <p>The Ministry of Culture and Education from 2001 to 2011 (accreditation number: 134/DIKTI/Kep/2001)</p> </li> <li class="show"> <p>The Ministry of Research and Higher Education for the period of 26 April 2017 to 26 April 2022 (accreditation number: 32a/E/KPT/2017)</p> </li> <li class="show"> <p>The Ministry of Education, Culture, Research, and Technology for 2022-2026 (Volume 28 (1) April 2022 to Volume 32 (2) August 2026 with accreditation number: 79/E/KPT/2023)</p> </li> </ol> <p align="justify">Since 2011, the journal has been indexed by Zoological Record by Thomson Reuters Clarivate Analytics, adding to its reputation and visibility in the scientific community. Moreover, in April 2012, the journal transitioned from publishing in the Indonesian language to publishing exclusively in English, making its content accessible to a broader international audience.</p> <p align="justify">Berkala Penelitian Hayati covers a wide range of topics in the field of biology, and it encourages the submission of original research, applied research, review articles, and educational articles. Authors are invited to submit authentic and unpublished works, not currently under review in other journals, ensuring the integrity and novelty of the content.</p> <p align="justify">The journal's scope includes but is not limited to the following areas of study: botany, zoology, ecology, microbiology, physiology, nanobiology, coastal biology, hydrobiology, neurobiology, genetics, developmental biology, biochemistry and molecular biology, biophysics, and other life sciences-related topics.</p> <p align="justify">Berkala Penelitian Hayati is available in online versions which is freely accessible and allows readers to download articles for easy access to the latest scientific research in the life sciences.</p> <p align="justify">The journal is indexed in various reputable databases, including DOAJ, Crossref, Google Scholar, Academia.edu, and EBSCO Host, ensuring that researchers and scholars can easily find and cite the published articles.</p> <h3>Founding and Historical Background</h3> <p align="justify">Prof. Drs. Bambang Irawan M.Sc., Ph.D., a Professor in the field of Population Biology and Carsinology at the Faculty of Science and Technology (FST), Airlangga University, initiated the publication of the journal in 1995. At that time, the journal was managed manually, including typing and printing. His contributions laid the foundation for the journal's growth and continued development as a significant platform for biological research dissemination.</p> <p align="justify">During that period, much research data in Indonesia was primarily presented in seminars and rarely documented or published in journals. The high costs associated with scientific journal publication, including editorial expenses and communication between authors and editors via postal services, posed significant challenges. Additionally, the availability of national journals was very limited. Recognizing these challenges, the need for an accessible and structured scientific publication led to the establishment of Berkala Penelitian Hayati.</p> <p align="justify">Overall, Berkala Penelitian Hayati serves as a valuable platform for researchers to share their findings, advancements, and knowledge in the diverse and ever-evolving field of biology.</p> https://berkalahayati.org/index.php/jurnal/article/view/858 2025-08-18T09:17:29+00:00 Eria Nada Ramadhan vironiramadhan@gmail.com Rio Risandiansyah a@yahoo.com Citra Destya Rahma Putri a@yahoo.com

<p>Miswak wood is empirically used to clean teeth, as it is known to have antibacterial activity mediated by its secondary metabolite . As a potential plant, miswak wood contains various secondary metabolite compounds, such as flavonoid terpenoid, steroid, alkaloid, saponin,&nbsp;and&nbsp;tannin. The levels and types of active compounds extracted from the extraction process depend on the nature of the solvent used.&nbsp; This study compares the total flavonoid levels of miswak wood with methanol, n-butanol, and ethyl acetate solvents. This study used an experimental design from an in vitro laboratory. This study uses samples of miswak wood extract extracted using the kinetic maceration method using methanol, n-butanol, and ethyl acetate solvents. Then, the extraction results will be qualitatively analyzed through phytochemical screening to see the presence or absence of flavonoid compounds, saponins, tannins, phenolics, alkaloids, terpenoids, and steroids, and quantitative phytochemical screening will be carried out to determine the level of flavonoid compounds in miswak wood extract using UV-vis spectrometry. Data analysis used non-parametric Kruskal-Wallis, followed by a post-hoc comparison test. Extract of miswak wood by kinetic maceration method showed positive for secondary metabolite compounds of flavonoids, alkaloids, terpenoids, phenolics, tannins in methanol, n-butanol, and ethyl acetate solvents, while saponins were only negative in ethyl acetate solvent. Determination of flavonoid compound levels showed ethyl acetate contained as much as 99.15 ± 8.14 mgEQ/g, then n-butanol as much as 62.08 ± 6.10 mgEQ/g, and methanol as much as 13.23 ± 7.47mgEQ/g significance test (P&lt;0.05). Post-hoc pairwise Wilcoxon test showed significant results (p&lt;0.05). This shows the type of solvent that influences flavonoid levels. The types of compounds that can be withdrawn by methanol and n-butanol solvents are more than the ethyl acetate solvent. The highest flavonoid levels were found in ethyl acetate solvent, and the lowest in methanol solvent.</p>

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